A., Chan, K., Bytautas, J., Kang, S., et al. Genetic risk disclosure was associated with increased motivation to recommend genetic testing to family and friends.īlanchette, P. In the MI-GENES study, motivation to participate in and perception of genetic testing among study participants were overall favorable.
Participants who initially received their GRS were more inclined to recommend genetic testing to family and friends (9.95 ± 1.88 vs. Perception of genetic testing was also favorable in both groups (15.29 ± 0.39 vs. 17.58 ± 0.83, p = 0.091), but participants who initially received their GRS indicated a greater desire to find ways to improve health as a reason for participation (OR: 0.53 (95%CI: 0.29, 0.94), p = 0.028). Overall, motivation to participate in genomic clinical trials was favorable and did not differ between the CRS and GRS groups (16.95 ± 0.82 vs. Linear and logistic regression were used for analysis.
Surveys on motivation to participate in and perception of genetic testing for CHD were administered at 3 months and treatment beliefs at 6 months following risk disclosure. In this study, participants at intermediate 10-year risk of CHD were randomized to receive either their estimated conventional risk score (CRS) alone, or a CRS and a genetic risk score (GRS), by a genetic counselor. Little is known about individuals’ motivation, perception, and treatment beliefs towards the use of genetic information in risk estimates for coronary heart disease (CHD).
0 kommentar(er)
